DH Templates

What is the feature of ribonucleotides that allows them to serve as templates for replication?

What is the feature of ribonucleotides that allows them to serve as templates for replication? Polypeptides can form extensive antiparallel structures—why can’t one polypeptide serve as a template for a specific, complementary polypeptide? May someone explain this to me in a easy to understand explanation. Thanks in advance!

Public Comments

1. well there are many points to take care of .one good reasoning is complementary base paring between A=T AND G=C this will arrange bases in an ordered systematic manner in the sense that if A does not pair with T and pairs with any other base the width of DNA at that point will be more or less than 20 angstroms thus the structure of entire DNA molecule will be under torsional pressure and eventually distorts. But it remains exactly as 20 angstroms when A=T G=C rule is maintained. so this complementarity keeps the things in track. In a polypeptide, at each point the side chains will interact with other molecules in surroundings and makes it difficult to be uniform. also all side chains are not uniform
2. Dear RNA is similar to DNA in typical structure except two major differences between RNA and DNA; that is, RNA contains uracil instead of thymine and ribose instead of deoxyribose in each of the nucleotides. In addition, unlike most DNAs, RNA is single -stranded and can for the hairpin loops found in single-stranded DNA. Because RNA lacks the regular double-helical structure, it does not follow Chargaff's rules. RNA has a number of specialized functions in the cell and most remarkable and different from DNA is that RNA is able to catalyze some chemical reactions. It was proved by Thomas Cech in 1980 in Tetrahymena protozoan that RNA can act as enzyme therefore he called it ribozyme and was awarded Nobel prize in 1989. It is only RNA Polymerase which can identify open naked bases and during replication of DNA, DNA Polymerase III recognizes primer synthesized by primase (a kind of RNA Polymerase). Check in http://bisbio.in